UniProtKB/Swiss-Prot

Ectodermal dysplasia 7, hair/nail type: A form of ectodermal dysplasia, a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures such as hair, teeth, nails and sweat glands, with or without any additional clinical sign. Each combination of clinical features represents a different type of ectodermal dysplasia. Ectodermal dysplasia of the hair/nail type is characterized by hypotrichosis and nail dystrophy without non-ectodermal or other ectodermal manifestations.

MalaCards based summary

Ectodermal Dysplasia 7, Hair/nail Type, is also known as ectd7, and has symptoms including hypotrichosis, dystrophic toenail and dystrophic fingernails. An important gene associated with Ectodermal Dysplasia 7, Hair/nail Type is KRT74 (Keratin 74). Affiliated tissues include skin.

OMIM

Some ectodermal dysplasias are here classified as congenital disorders characterized by abnormal development in 2 or more ectodermal structures (hair, nails, teeth, and sweat glands) without other systemic findings. Ectodermal dysplasia of the hair/nail type is a rare congenital condition characterized by hypotrichosis and nail dystrophy without nonectodermal or other ectodermal manifestations. (614929)