OMIM

Age-related hearing impairment (ARHI), or presbycusis, is the progressive bilaterally symmetric deterioration of hearing ability that occurs with aging. Studies of the cochlea in many animal species and of the histopathology of human temporal bones have shown that stria vascularis volumes and spiral ganglion cell, inner hair cell, and outer hair cell populations, as well as many other cochlear cell types and structures, undergo age-related degeneration. Environmental risk factors for ARHI include noise exposure, smoking, ototoxic medication, and cardiovascular disease. Heritability estimates vary between 0.25 and 0.75 depending on, among other factors, study design (family vs twins), age range of the study population, and the phenotype studied (Huyghe et al., 2008). (612448)

MalaCards based summary

Age-Related Hearing Impairment 1, also known as presbycusis 1, is related to age-related hearing loss. An important gene associated with Age-Related Hearing Impairment 1 is ARHI1 (Age-Related Hearing Impairment 1). The drug Pharmaceutical Solutions has been mentioned in the context of this disorder. Affiliated tissues include bone.